Compare Multiple Drug Targets at Once

25th February 2025
Posted by: Breige McBride
Category: Uncategorised

If you are a drug development researcher, you know how vital choosing the right the drug target is to overall development success. You will also know that choosing a drug target isn’t a straightforward or easy process. But comparing drug targets can be, thanks to Target Triage.

Target Triage gathers and organises information about potential drug targets so you can easily compare relevant information about each target, at a glance. It takes drug target information from diverse public sources and displays it in an interactive HTML report, designed to allow you to fully explore the collected data.

What Information Does a Target Triage report contain?

With a Target Triage report, you can view the following information (where publicly available) about multiple drug targets all in one place:

Protein metadata, RNA expression and protein level data in normal human tissues and cell types
RNA expression in non-human species including mouse (M. musculus), rat (R. norvegicus), dog (C. lupus), pig (S. scrofa) and Crab-eating macaque (M. fascicularis)
Gene Ontology (GO) terms and Reactome pathways describing function
Known evidence of association with disease traits
Information on compounds in development that target the proteins and their clinical stage
Documented genome variants for each gene and associated population frequencies and impact

Having all of this information available in one place removes the need for you to sift through multiple databases to find and organise the information you need.

Applications of Target Triage

As Target Triage contains a wealth of functional information about your targets of interest, it can be used in a variety ways.

Target Triage allows you to:

Confidently choose the most suitable candidate target to validate
De-risk your program by selecting the target that has the best chance of being successful
Support your primary target by discovering competing programmes and their stage, the most appropriate drug modality to impact target and identification of associated indications
Do due diligence on already selected targets, by gathering available information on tissue expression (for on target off tissue considerations) and model species homology to help select the best species

Designed for Easy Drug Target Comparisons

When we designed the Target Triage report, we aimed to make comparisons between different targets as easy as possible. To illustrate this, here is snapshot taken from a sample Target Triage report:

Image shows a screenshot from a sample Target Triage Report

The image above shows phenotypic traits, Gene Ontology and Reactome pathway information for two genes. As you can see, the layout of the information allows you to see at a glance which phenotypic traits, Gene Ontology and Reactome pathways the genes have in common, as well as those individual to each gene. This is just one example of how Target Triage is designed to make comparisons as easy as possible. If you would like to see more, request a sample Target Triage report using the form below:

Sample report request - Target Triage

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How Does Target Triage Work?

It’s quick and simple. Just tell us your targets of interest and we will create your Target Triage report, within the following timescales:

This is an image of a table displaying the following Target Triage timeline information: Up to 5 targets: ~1 week 6-10 targets: Between 1 and 2 weeks More than 10 targets: Tell us how many targets for a timeline confirmation

Already Have Some Drug Targets in Mind?

Just fill in the form below and a member of our team will get back to you with a quote!