Drug Repurposing
We can help maximise the value of your drug pipeline by repurposing or repositioning your drug or novel therapeutic for new indications. We have strong experience with identifying in silico new potential indications for existing drugs, reducing the cost and time of downstream wet lab validation.
How we can help with drug repurposing
By combining our expertise in bioinformatics analysis with our knowledge in drug repurposing, we can support your research no matter the therapeutic area you target. Our bioinformatics services can help repurpose drugs by:
- Signature generation of compound effects
- In silico assessment of potential indications for repurposing using on- and off target effects
- Data landscaping and mining for markers in potential indications of interest
- Our bespoke solutions utilise state-of-art approaches, tailored to the data types and requirements of each project.
Selected Publications
For more publications, visit our dedicated Publications page.
Getting Your Data Ready For Analysis
We can analyse:
- Recent data, generated within your own laboratory or that of a 3rd party provider
- In-house historic data
- Data sourced from the public domain.
While we prefer to receive data in the raw format (eg .CEL files) we can also receive pre-normalised files.
If you have yet to generate the data, we can help by arranging for the generation of your data through one of our preferred laboratory service partners. Alternatively, we are able to source and mine data from available databases. We are happy to work with you at every stage of your study to ensure the best outcome for your research.
Our Reports
Our analysis reports at Fios are provided as an HTML link hosted on our secure server. The secure link leads the user to a password-protected HTML document which is clickable, searchable and dynamic. This format allows you to easily interrogate and explore your data. Additionally, all methods, tools and thresholds are fully documented within the report.
At Fios Genomics, we are completely data driven. Whatever your research area, we offer support at every stage of your research and for different purposes:
Discovery
Selecting the correct targets and/or the correct indication is essential for development success. We help support the process with robust analysis of historic or new data.
Preclinical Research
We help in experimental design and statistical analysis and guide our clients in making informed decisions during the preclinical stage.
Clinical
Research
We offer a comprehensive analysis approach for augmenting clinical trial outcomes, ensuring you get the most information out of your research.
Drug Repurposing
We have strong experience with identifying in silico new potential indications for existing drugs, reducing the cost and time of downstream wet lab validation.
