Infections and Vaccines
The research of new vaccines has never been so intensive and fast-paced. Our analysts can help you to answer key questions and reduce wet lab work to hasten the discovery process.
How we can help your infections and vaccine research
By combining our expertise in bioinformatics analysis with our extensive knowledge in the analysis for infections and vaccine research, we can support your research at every stage of the drug development from pre-clinical to clinical stage. Our bioinformatics services can help with:
- Identifying mechanism of resistance to treatment for bacterial and viral species
- Monitoring mutation profiles of pathogens
- Target and lead identification and validation
- Identifying biomarkers for measurement of drug efficacy and mechanism of action
- Predicting biomarkers for stratification/classification of patient response to drug
- SNP genotype analysis & DNA sequence analysis for the detection of novel SNPs implicated in disease or response to drugs
Our bespoke solutions utilise state-of-art approaches, tailored to the data types and requirements of each project.
Selected projects we have helped with
- Correlation of protein levels with patient response to treatment to identify predictive biomarkers
- Analysing expression of diseased vs. normal samples to gain insight into potential pathological mechanisms.
- Analysis of bacterial strains to identify mechanisms of antibiotic resistance
Selected Publications
For more publications, visit our dedicated Publications page.
Getting Your Data Ready For Analysis
We can analyse:
- Recent data, generated within your own laboratory or that of a 3rd party provider
- In-house historic data
- Data sourced from the public domain.
While we prefer to receive data in the raw format (eg .CEL files) we can also receive pre-normalised files.
If you have yet to generate the data, we can help by arranging for the generation of your data through one of our preferred laboratory service partners. Alternatively, we are able to source and mine data from available databases. We are happy to work with you at every stage of your study to ensure the best outcome for your research.
Our Reports
Our analysis reports at Fios are provided as an HTML link hosted on our secure server. The secure link leads the user to a password-protected HTML document which is clickable, searchable and dynamic. This format allows you to easily interrogate and explore your data. Additionally, all methods, tools and thresholds are fully documented within the report.
At Fios Genomics, we are completely data driven. Whatever your research area, we offer support at every stage of your research and for different purposes:
Discovery
Selecting the correct targets and/or the correct indication is essential for development success. We help support the process with robust analysis of historic or new data.
Preclinical Research
We help in experimental design and statistical analysis and guide our clients in making informed decisions during the preclinical stage.
Clinical
Research
We offer a comprehensive analysis approach for augmenting clinical trial outcomes, ensuring you get the most information out of your research.
Drug Repurposing
We have strong experience with identifying in silico new potential indications for existing drugs, reducing the cost and time of downstream wet lab validation.
