At Fios, we have experience in handling and analysing datasets from studies investigating fibrosis, mesothelioma, COPD, and lung cancer amongst others.
How We Can Help Your Respiratory Research
By combining our expertise in bioinformatics analysis with our extensive knowledge in the oncology area, we can support your research at every stage of the drug development process from pre-clinical to clinical. Our bioinformatics services can help with:
- Target and lead identification and validation
- Identifying biomarkers for measurement of drug efficacy and mechanism of action
- Predicting biomarkers for stratification/classification of patient response to drug
- SNP genotype analysis & DNA sequence analysis for the detection of novel SNPs implicated in disease or response to drugs
Our bespoke solutions utilise state-of-the-art approaches, tailored to the data types and requirements of each project.
We were very pleased with the service provided by Fios Genomics. In particular, the Fios team were flexible and willing to spend time understanding our specific project needs and the key scientific questions we were asking of the experiments. They tailored the data output in a way that specifically addressed these questions, which was really helpful. The data package was Web-based and interactive and we were delighted with the way it was presented and explained to us. We will certainly work again with the Fios team for any future projects.
Every time our clients work with us, they benefit from:
- A dedicated analyst backed by an experienced team to curate all data, identify the most appropriate statistical approach to take and provide a biological interpretation of results
- An interactive data analysis report, internally peer-reviewed, including all analysis methods and results
- Post-report follow ups: upon receipt of our data analysis report, we arrange a teleconference so that our lead analyst can talk through the results
- Access to large capacity computing and secure data storage facilities
Selected Projects We Supported
- Analysis of pharmacogenomics data from a Phase 2B trial in asthmatic patients
- Investigation into fibrotic pathways and gene expression changes regulated by TGFβ and L-13
- Individual dataset analysis of patient demographic, response, genotype and miRNA expression data from patients with COPD, and subsequent integration and congruence analysis
- Identification of early markers for lung cancer risk
At Fios Genomics, we are completely data driven. Whatever your research area, we offer support at every stage of your research and for different purposes:
Discovery
Selecting the correct targets and/or the correct indication is essential for development success. We help support the process with robust analysis of historic or new data.
Preclinical Research
We help in experimental design and statistical analysis and guide our clients in making informed decisions during the preclinical stage.
Clinical
Research
We offer a comprehensive analysis approach for augmenting clinical trial outcomes, ensuring you get the most information out of your research.
Drug Repurposing
We have strong experience with identifying in silico new potential indications for existing drugs, reducing the cost and time of downstream wet lab validation.
